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DL-mandelic acid suppliers & manufacturers

DL-Mandelic Acid

Product Specifications and brief introduction
L-mandelic acid(S-mandelic acid), CAS 17199-29-0
DL-Mandelic Acid, CAS 90-64-2/ 611-71-2
Mandelic Acid CAS 611-71-2

DL-Mandelic Acid  is an aromatic alpha hydroxy acid with the molecular formula C6H5CH(OH)CO2H. It is a white crystalline solid that is soluble in water and polar organic solvents. It is a useful precursor to various drugs. Since the molecule is chiral, it exists in either of two enantiomers as well as the racemic mixture, known as paramandelic acid.

DL-Mandelic Acid was discovered while heating amygdalin, an extract of bitter almonds, with diluted hydrochloric acid. The name is derived from the German “Mandel” for “almond”. Derivatives of mandelic acid are formed as a result of metabolism of adrenaline and noradrenaline by monoamine oxidase and catechol-O-methyl transferase.

DL-Mandelic Acid is usually prepared by the acid-catalysed hydrolysis of mandelonitrile,which is the cyanohydrin ofbenzaldehyde. Mandelonitrile can also be prepared by reacting benzaldehyde with sodium bisulfite to give the corresponding adduct, forming mandelonitrile with sodium cyanide, which is hydrolyzed.

DL Mandelic Acid Function

Mandelic acid has a long history of use in the medical community as an antibacterial, particularly in the treatment of urinary tract infections. It has also been used as an oral antibiotic, and as a component of ‘chemical face peels’, along with other alpha-hydroxy acids (AHAs). The drugs cyclandelate and homatropine are esters of mandelic acid.

DL Mandelic Acid Use

DL-Mandelic Acid has a long history of use in the medical community as an antibacterial, particularly in the treatment of urinary tract infections. It has also been used as an oral antibiotic, and as a component of “chemical face peels”, along with other alpha-hydroxy acids (AHAs).

  • The drugs cyclandelate and homatropine are esters of mandelic acid.
  • In pharmaceutical industrial, Pharmaceutical intermediate DL-Mandelic Acid can be used as an
  • intermediate in the synthesis of methyl benzoylformate,Cefamandole,
  • hemangiectasis chemical-Cyclandelate, eyedrops-Hydrobenzole,
  • Pemoline. It can also be used as preservative, chemical reagent,
  • Intermediate for dye and pesticide, etc..

Package and Storage of Pharmaceutical intermediate DL-Mandelic Acid:

  • Store in cool and dry places, far away from fire and heat.
  • It is usually packed in 25KG fiber drum or paper bag, or according to
    customers’ requirement

DL-Mandelic Acid msds

Tests Specifications Results
Density / Assay 98.5%   to 101.0% 99.70%
Appearance White   crystalline powder White   crystalline powder
Odor   and taste Characteristic Complies
Specific   rotation -155±2° Complies
DL-Mandelic Acid Melting  point range / boiling point 130   to 134°C 131   to 133°C
Loss   on drying MAX.   0.5% 0.3%
Residue   on ignition MAX.   0.2% 0.05%
Heavy   metals MAX.10   PPM Complies
Microbiology   control

Total   Plate Count

Yeast   & Mold

E.Coli

S.   Aureus

Salmonella

 

MAX.1,000cfu/g

MAX.100cfu/g

Negative

Negative

Negative

 

NMT   1,000cfu/g

NMT   100cfu/g

Complies

Complies

Complies

About us

Nanjing Joint Friends Chemical Co.,Ltd, founded in 2002,is a professional supplier specializing in R&D and natural active ingredients of plant extracts and fermentation production. Since the establishment our company has continuously made innovation In January 2006,

Our company investd in construction of GMP standard plant with an area of 8,000 square meters, and controls audit in strict accordance with the production process index of the State Pharmacopoeia Commission.

In 2007, our company actively respond to the national innovation and encouragement policies, participated in R&D and was awarded the provincial advanced unit. In the same year, our company developed more than 30 types of products, and won recognition from domestic and foreign customers owing to the superior quality, we also begin to establish our fermentation plant and meet a good cooperation with PolyU(HKPU),  also begin our talent strategy.

Now our company has a staff of over 100 people, and develops more than 100 types of products. Our products cover the industries such as medicine, food, cosmetics, etc.

To know more about our products, please check the catalog as below:

 PRODUCTS CATALOGUE OF KONO CHEM
NO NAME SOURCE PURITY STANDARD PACKAGE
001 Coenzyme Q10 Tobacco 10%-99% USP32 Drum & Bag
002 L-Glutathione Yeast 99% JP Drum & Bag
003 Ecdysterone cyanotis arachnoidea 50%-98% CP2005 Drum & Bag
004 Capsaicin Chili pepper 10%-95% USP32 Drum & Bag
005

006

Matrine

Oxymatrine

Sophora flavescens

Sophora flavescens

1%-98%

1%-98%

USP32

USP32

Drum & Bag

Drum & Bag

007 Raspberry Ketone Raspberry 99% USP32 Drum & Bag
008 Oleanolic Acid ligustrum lucidum ait. 98% CP2010 Drum & Bag
009 Ursolic Acid Eriobotrya japonica(Thunb.)Lindl 1%-98% CP2010 Drum & Bag
010 Chlorogenic Acid Eucommia ulmoides Oliv. 1%-98% CP2010 Drum & Bag
011 Usnic Acid Usneaceae 98% CP2010 Drum & Bag
012 Shikimic Acid Illicium verum Hook.f.) 98% USP32 Drum & Bag
013 Sinomenine Hcl Sinomenium actum Rehd.et 98% USP32 Drum & Bag
014 Berberine Hcl Coptis chinensis Franch 98% CP2010 Drum & Bag
015

016

Silymarin

Silybinin

Milk thistle

Milk thistle

80%

98%

EP6

EP6

Drum & Bag

Drum & Bag

017

018

019

020

021

022

023

Lutein

Zeaxanthin

Lycopene

Beta carotene

Canthaxanthin

Fucoxanthin

Astaxanthin

Marigold flower

Marigold flower

Tomato

Carrot

Algae

Brown algae

Haematococcus pluvialis

2%-98%

5%-20%

1%-10%

1%-98%

1%-10%

1%-10%

1%-10%

USP32

IN HOUSE

USP32

USP32

USP32

IN HOUSE

IN HOUSE

Drum & Bag

Drum & Bag

Drum & Bag

Drum & Bag

Drum & Bag

Drum & Bag

Drum & Bag

Advantage

Rich experience in loading a great amount of containers in Chinese sea port;
Fast shipment by well-reputed shipping line;
Packaging with pallets according to buyers’ special request;
Cargoes together with container sales service available;
Rich experience in Korea, India & Europe export;